PATHOLOGY

 

Biopsies

 

Operational materials

 

CYTOLOGY

 

Conventional Pap smear

 

Thin prep smear (with cytospin)

 

Fine needle aspiration biopsy (FNAB)

 

Body fluids (with cytospin)

 

FROZEN SECTİON

 

Intraoperative diagnosis

 

AUTOPSY

 

For determening of the cause of dead.

 

HISTOCHEMISTRY

 

Hematoxylen-Eosin: "In rutin sections"

 

Papanicolaou; "In smears and other cytologic materials”

 

May-Grünwald-Giemsa; "In FNABs"

 

May-Grünwald-Giemsa for tissues: "for Helicobacter-pylori in gastric biopsies"

 

PAS/AB pH 2,5: "for intestinal metaplasia in gastric biopsies”

 

Gention viole and Congo red; "for Amyloid"

 

Mucicarmine; "for mucin"

 

Silver impregnation for reticulum; "in liver and bone marrow biopsies"

 

Perls method for ferric iron; “in marrow biopsies"

 

Masson-trichrome; "in soft tissue tumors".

 

Grocott's; for detecting fungal microorgamisms.

 

Ziehl Neelsen; for detecting asidoresistant bacteria.

 

 

 

 And Others, totally 20 histochemical kits.

 

IMMUNOHISTOCHEMISTRY

 

For differential diagnosis; Cytokeratins, EMA, Vimentin, LCA (CD45), GFAP, S-100, etc.

 

For treatment; Estrogen-Progesteron receptor, c-erb-B2 (Her2 neu) etc.

 

Proliferation marker; Ki-67, cyclinD-1.

 

Lymphoma diagnosis and typing; CD20, CD3, CD5, CD10, CD30, CD15, cyclinD-1, CD23, bcl-2, bcl-6, TdT, cylinD-1, ALK etc.

 

For metastatic tumors; Thyroglobulin, GCDFP-15, PLAP, AFP, CK7, Melan-A, CK19, CK20, TTF-1 etc.

 

For keratin profile; AE1/AE3, CK5/6, 34BE12, CK18, CK19, CK20.

 

For neurendocrin differentiation: CD56, synaptophysin, chromogranin-A.

 

For microorganisms: HHV8, CMV.

 

 

 

 

GENETICS

 

HPV typing by PCR; In paraffin blocks or in liquid based PAP smear solution.

 

k-ras; in colon carcinoma, lung carcinoma.

 

HER2, EGFR by FISH